I shot twice at my largest coues and took him with the second shot at 394 yds. My Weatherby 300 mag was sighted in for 300 yards and shoots better than my abilities. Took two at just under 300 and two more at less than 100 running away. Never lost a coues yet! My son (age 15) took one last year at 304 yds the last 45 mins of the hunt. Most important thing, IMO, is a super steady rest and good shooting form and practice, practice practice!!!